Functional and Comparative Genomics

Course Material for Bachelors Students in Genomic Sciences at Center for Genomic Sciences as part of

the course "Introduction to Bioinformatics"

The course consists of three classes on Functional to Comparative Genomics (Click the links below to obtain the slides and lecture notes)

a) Functional Genomics I (where we would be discussing notions of homology and subtypes, paralogy and subtypes, functional classes based on sequence, physiological roles and more general functional descriptions (Gene ontology))

b) Functional Genomics II (where we would be discussing about Functional classification schemes like Kegg, protein domains, motifs and classification schemes, Protein super families based on folds, Issues with annotations of genomes. We will touch upon issues and challenges in metagenomics in the concluding session.)

c) Comparative Genomics in Prokarya ( Here we will be talking about inference of gene function from genomic context and introduce concepts like Gene order conservation, gene fusion, Phylogenetic profiles and operon predictions).

You can obtain the complete lecture in the form of slides and the exercises given in the class in the respective links above.